Showing posts with label FAQ's. Show all posts
Showing posts with label FAQ's. Show all posts

Wednesday, May 30, 2012

What is special about DNA?



DNA is a chemical that occurs inside every cell of a person’s body. The DNA is contained in 22 pairs of structures known as chromosomes, shaped like an X, plus an extra pair – the sex chromosomes – which determine whether someone is male or female. In this final pair, women have two X chromosomes, but men have one X and one Y chromosome. Each chromosome consists of two long strings of chemical letters, twisted together in the famous shape of the double-helix. The chemical letters occur in pairs as rungs on this twisted chemical ladder. The four chemical letters of the genetic code spell out instructions to the cell about how to make the proteins that allow the human body to grow and function normally. The parts of the DNA sequence that contain the instructions for making proteins are known as genes. 
DNA is useful to identify an individual because everyone’s genetic code is thought to be unique, unless they have an identical twin. The string of chemical letters in a person’s DNA can therefore act like a unique bar code to identify them. Because a person inherits half their DNA from their mother and half from their father, it can also be used to identify their relatives. Close relatives have a DNA sequence that is more alike than distant relatives or than someone who is unrelated.
 Biological identifiers such as DNA, fingerprints, iris scans and digital photographs are known as ‘biometrics’. In recent years there has been a lot of interest in developing biometrics to track and identify individuals as they enter or leave different countries or as they use public or private services, such as banks, computers, workplaces or hospitals.
Unlike iris scans and photographs, DNA and fingerprints can be left wherever a person goes: for example, on a glass or cup that they have been drinking from. This means that they can be used to track individuals – i.e. to find out whether they have been at a particular place, such as a crime scene or meeting place – where there might not be a scanner or a camera.

DNA differs from fingerprints in two main ways:



• Because DNA has a biological function, some of the information in a person’s DNA may be relevant to their health or other physical characteristics, such as their eye colour.
• Because DNA is shared with relatives, a person’s DNA can be used to help identify their parents or children and perhaps more distant relatives.
 However, DNA profiles used by the police are not based on the whole sequence of someone’s DNA, but only on parts of it. This means that the information contained in them is more limited than that contained in a person’s whole genetic make-up.

Tuesday, May 29, 2012

How do you reduce the contamination of evidence?


1.     How do you reduce the contamination of evidence?
The risk of contamination of evidence is minimized by applying the following precautionary steps:

*     Using chain of custody labels
*     Opening each package in an area other than where it was originally sealed
*     Repackaging each item of evidence as soon as it has been analyzed
*     Assiduously using logging systems
*     Minimizing the number of people handling the evidence
*     Storing packaged evidence in a dedicated secure area.

Muscles


1.     Briefly highlight the contraction of the smooth muscles
Calcium ions come from outside the cell. They bind to calmodulin in the cytosol and then bind to an enzyme on myosin called Myosin Light Chain Kinase which uses ATP to transfer a phosphate to myosin. The phosphate activates the myosin which then forms cross bridges with actin. When ca++ is pumped out of the cell, the phosphate gets removed from myosin by another enzyme. Myosin becomes inactive and the muscle relaxes.
2.     State the characteristics of smooth muscle
-more actin than myosin
-no striations
-spindle shaped
-no sarcomeres
-fatigue resistant
-activation is involuntary
-innervation is by ANS
-located in blood vessels, gastro-interstinal tract, urinary bladder, respiratory tract, iris of the eye and reproductive organs
-External longitudinal layer-runs parallel to the organs long axis and shorten and widen the lumen when it contracts
-Internal circular layer-runs around the circumference of the organs axis lengthens the tube but narrows the lumen when contracted
3.     State the characteristics of skeletal muscles
-Excitability- capacity of the muscle to respond to stimuli
-Extencibility-abilty of the muscle to stretch back to its original length
-Contractility- ability of the muscle to shorten and generate a pulling force
 -Elasticity- ability of the muscle to recoil to its original resting length after stretch.